Making his debut on August 2012 aged 22 Lopez has a so far mixed record of 6-1-0. Although he has been beaten previously, the future looks positive. The longest KO streak that Lopez has ever had is 4 throughout his 7 fights and his longest winning streak is 5 wins. This started on August 2012 and came to an end on October 2013.
Lopez proved he was made for the pro ranks in his debut against Alejandro Ayala, becoming the first person in Ayala's 0 fights to stop him. The fight ended in round 3 of 4. Continuing on from his successful debut, Lopez won his next 4 fights taking his record to 4 wins.
Next was Jason Tresvan on March 30th, 2013 where Lopez took the win continuing his unbeaten streak. Becoming the first person to stop Jason Tresvan, Lopez beat Tresvan via TKO in the 2nd round of a 4 round fight. Lopez's win streak of 2 rose to 5 following 3 great wins, becoming the 6th person to defeat Julio Chavez, first to stop Lance Dickelman and first to stop Chris Rael.
On May 17th, 2014, Lopez took on and was defeated by Cameron Kreal in his first career defeat meaning his career tally went to 5-1-0. Taking the first setback of his career, the May 17th, 2014 Kreal defeat went the full distance and ended via MD.
Ensuring he added another win to his tally, Manuel damairias Lopez defeated Javier Rodriquez on June 21st, 2014 in his latest fight. In 2014 Lopez fought and defeated his next opponent Javier Rodriquez. In a successful fight, Lopez was the 3rd person to go the distance with Rodriquez.